Signal Transduction Research TrendsNova Publishers, 2007 - 311 páginas Signal transduction is any process by which a cell converts one kind of signal or stimulus into another. Processes referred to as signal transduction often involve a sequence of biochemical reactions inside the cell, which are carried out by enzymes and linked through second messengers. In many transduction processes, an increasing number of enzymes and other molecules become engaged in the events that proceed from the initial stimulus. Responses of cells to environmental signals, toxins and stressors have profound implications for diverse aspects of human health and disease including development, cystic fibrosis, diabetes, asthma, heart, autoimmune diseases and cancer. The delineation of the signal transduction pathways affected in these and other complex human diseases are likely to present new avenues for therapeutic intervention and understanding of human disease mechanisms. |
Contenido
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| 17 | |
The Peptide Strategy as a New Approach to the Study of G Proteincoupled Signaling Systems | 45 |
Cadherin Signaling in Vascular Cells Tcadherin is a new Player | 95 |
Time Windows of Hedgehog Signaling in the Craniofacial and Vascular Development Analyses Using Mouse Whole Embryo Culture System | 131 |
The Ror2 Receptor Tyrosine Kinase | 171 |
Nuclear Calcium Signalling The Nuclear Envelope Store and the Regulation of Transcription | 187 |
Regulation of Extracellular Signal Communications at the Cortical Network Level by Intracellular Signal Communications in the Brain | 207 |
New Research on Signal Transduction in Response to Bacteroides Fragilis Enterotoxin | 221 |
Innate Immune Signalling Pathways and Viral Recognition New Perspectives | 249 |
Neurosignaling Mechanisms and Environmentalinduced Neurobiological Activities | 265 |
| 293 | |
Términos y frases comunes
acid action activation addition adhesion amino angiogenesis apoptosis associated binding Biochem Biol brain C-terminal Ca2+ cadherin calcium cancer cells changes Chem complex concentration containing corresponding coupling craniofacial cultured cyclopamine cytoplasmic defects dependent derived differentiation domain drug effects embryos endothelial epithelial cells estrogen receptor et al expression factor Figure formation function G protein gene growth hedgehog Hh signaling hormone human identified important increased indicate induced inhibition interaction intracellular involved kinase leads levels ligand mechanisms mediated membrane mice modulate molecular molecules mouse mutations Nature neural crest neural tube neurons nuclear nucleus peptide phenotype phosphorylation positive present production promoter recent region regulation release reported residues response role Ror2 selective showed shown signal transduction signaling pathways specific stimulation structure studies subunit suggesting T-cadherin targeted therapy tissues transcription tumor tyrosine kinase vascular
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